Tirzepatide is a medication used to treat type 2 diabetes and obesity. It is a glucagon-like peptide-1 receptor agonist (GLP-1RA) and glucose-dependent insulinotropic polypeptide (GIP), which means it activates receptors of hormones secreted from the intestine (glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)) to reduce appetite and food intake. This medication helps to regulate blood sugar levels by stimulating insulin secretion and reducing glucagon secretion. It also slows down the rate at which food is absorbed in the stomach, which can help reduce appetite and promote weight loss. Studies find that Tirzepatide can be more effective for weight loss and has less side effects than semaglutide. It is often used as another option in patients who cannot tolerate the GI side effects of semaglutide.